Ketamine is a white, crystalline powder or clear liquid. Buy Ketamine HCL Crystal powder online at affordable prices. Ketamine is a rapid-acting anesthetic that can produce anesthesia while maintaining skeletal muscle tone, laryngeal-pharyngeal reflexes, and cardiovascular and respiratory stimulation
Synonyms of Ketamine Powder:
(+/-)-2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone; Ketalar®, Ketaject®, Ketaset®, Vetalar®; K, Special K, Vitamin K, Lady K, Jet, Super Acid, Bump, Special LA Coke, KitKat, Cat Valium. ketamine powder, Buy ketamine powder online, Order ketamine online.
Source of Ketamine Powder:
Available by prescription only, and is commercially available as a veterinary anesthetic. It is difficult to synthesize clandestinely and is usually stolen from veterinarian offices or diverted from legitimate pharmaceutical sources in liquid form. Ketamine is currently a schedule III controlled substance in the US.
Drug Class: Ketamine Powder
Dissociative anesthetic, hallucinogen, psychotomimetic.
Medical and Recreational Uses:
Primarily used in veterinary applications as a tranquilizer. Also used as an anesthetic induction agent for diagnostic and surgical procedures in humans, prior to the administration of general anesthetics. Occasionally used as a short-acting general anesthetic for children and elderly patients. Recreationally used as a psychedelic and for its dissociative effects.
Potency, Purity, and Dose:
Ketamine is available as a racemic mixture with the S-(+)- isomer being more potent than the R-(-)- isomer.
Commercially supplied as the hydrochloride salt in 0.5 mg/mL and 5 mg/mL ketamine base equivalents.
The liquid from injectable solutions can be gently heated to evaporate the water, leaving a white powder (ketamine hydrochloride) which can be snorted or orally ingested.
Recreational doses are highly variable. Common doses are 25-50 mg intramuscularly, 30-75 mg snorting, and 75-300 mg oral.
Further, Snorting a small line (“bump”, 30-50 mg) usually results in a dreamy effect. Order ketamine online.
Bioavailability following an intramuscular dose is 93%, intranasal dose 25-50%, and oral dose 20±7%. Also, The plasma half-life is 2.3 ± 0.5 hours. Oral administration produces lower peak concentrations of ketamine, but increased amounts of the metabolites norketamine and dehydronorketamine. Ketamine and its metabolites undergo hydroxylation and conjugation. Norketamine produces effects similar to those of ketamine. There are no significant differences between the pharmacokinetic properties of the S-(+) and R-(-)-isomers.
Molecular Interaction / Receptor Chemistry:
Cytochrome P450 3A4 is the principal enzyme responsible for ketamine N-demethylation to norketamine, with minor contributions from CYP2B6 and CYP2C9 isoforms. Potential inhibitors of these isoenzymes could decrease the rate of ketamine elimination if administered concurrently, while potential inducers could increase the rate of elimination.
Interpretation of Blood Concentrations:
There is no direct correlation between ketamine concentrations and behavior. Drowsiness, perceptual distortions, and intoxication may be dose-related in a concentration range of 50 to 200 ng/mL, and analgesia begins at plasma concentrations of about 100 ng/mL.